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In the theory for allergic desensitization,which immunoglobulin blocks the allergen from binding with IgE?


A) IgE
B) IgG
C) IgA
D) IgD
E) IgM

F) All of the above
G) A) and C)

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Allergic reactions to penicillins are considered a/n _____ hypersensitivity.


A) T-cell-mediated
B) antibody-mediated
C) immune complex-mediated
D) immediate
E) Both T-cell-mediated and antibody-mediated are correct.

F) B) and D)
G) D) and E)

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A chronic,local allergy such as hay fever is considered


A) delayed.
B) T-cell-mediated.
C) atopic.
D) antibody-mediated.
E) systemic anaphylactic.

F) All of the above
G) B) and D)

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C

DiGeorge syndrome is the result of


A) autoantibodies.
B) delayed hypersensitivity.
C) congenital absence or immaturity of the thymus gland.
D) failure of B-cell development and maturity.
E) a genetic defect in the development of both T cells and B cells.

F) A) and D)
G) C) and E)

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Tissue transplanted from one body site on a patient to a different body site on that patient is called a/an


A) isograft.
B) autograft.
C) allograft.
D) xenograft.
E) hypograft.

F) C) and D)
G) A) and D)

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Allergic patients receiving small,controlled injections of specific allergens are undergoing


A) desensitization.
B) sensitization.
C) tissue matching.
D) degranulation.

E) B) and C)
F) B) and D)

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Which of the following is not a theory to explain the origin of autoimmune diseases?


A) sequestered antigen theory
B) forbidden clone theory
C) molecular mimicry theory
D) theory of bystander effect
E) All the choices are currently being investigated as possible explanations.

F) A) and C)
G) None of the above

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A second encounter with an allergen that causes a response is called the _____ dose.


A) sensitizing
B) provocative
C) allergic
D) hypersensitivity
E) desensitizing

F) A) and E)
G) A) and B)

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B

Epinephrine


A) is an antihistamine.
B) reverses constriction of airways.
C) causes desensitization.
D) inhibits the activity of lymphocytes.

E) All of the above
F) A) and B)

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John,a Peace Corps worker in the country of Mali in Africa,was in a car accident while traveling through a rural area.He was treated at a tiny rural hospital,and due to his loss of blood required a transfusion.John is B- blood type and has never received a transfusion before.Which statement is correct regarding this scenario?


A) He can safely receive O- blood even though he makes anti-A antibodies.
B) He can be give types O or B,no matter whether Rh- or Rh+.At this point in time,he does not have anti-Rh antibody.O has no antigens on the blood cells,so he is also safe to receive that type in addition to his own B type.
C) He can be given A+ blood type,in addition to B+.Rh- means that he makes no antibody to Rh.
D) The preferred blood type to give John,in addition to his own B type blood,would be AB.Both types of blood have the B antigen on the cells,so they would correspond to his own antigens.As for Rh,he can receive only Rh- blood since he would have a reaction against Rh+.

E) C) and D)
F) None of the above

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Which event is the process of releasing chemical mediators?


A) degranulation
B) bonding of allergen to adjacent IgE binding sites on mast cells and basophils
C) binding of IgE by the Fc region to mast cells and basophils
D) histamine acts on smooth muscle
E) prostaglandins cause vasodilation and increased vascular permeability

F) C) and D)
G) B) and C)

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An antihistamine will


A) inhibit the activity of lymphocytes.
B) bind to histamine receptors on target organs.
C) block synthesis of leukotrienes.
D) relieve inflammatory symptoms.
E) reverse spasms of respiratory smooth muscles.

F) A) and C)
G) B) and C)

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An example of a secondary acquired immunodeficiency is


A) AIDS.
B) adenosine deaminase (ADA) deficiency.
C) DiGeorge syndrome.
D) agammaglobulinemia.
E) SCID.

F) B) and D)
G) A) and E)

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Place these events in the pathogenesis of contact dermatitis in order,with 1 being the first step. - chemical absorbed through skin - antigen identified by dendritic cell - cytokine chemicals attract macrophages,dendritic cells,and cytotoxic T lymphocytes to site of antigen - sensitized T lymphocytes recognize antigen and make cytokine chemicals -chemicals released from phagocytic cells and cytotoxic T cells,resulting in host tissue damage

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1 chemical absorbed through skin
2 antig...

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Severe combined immunodeficiencies (SCIDs) are due to


A) autoantibodies.
B) delayed hypersensitivity.
C) congenital absence or immaturity of the thymus gland.
D) failure of B-cell development and maturity.
E) a genetic defect in the development of both T cells and B cells.

F) A) and E)
G) B) and D)

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Contact dermatitis involves


A) a sensitizing and provocative dose.
B) an allergen entering the skin.
C) T lymphocytes secreting inflammatory cytokines.
D) the production of itchy papules and blisters.
E) All of the choices are correct.

F) A) and D)
G) B) and C)

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All of the following can result in acquired immune deficiency except


A) malnutrition.
B) stress.
C) pregnancy.
D) bacterial infection.
E) radiation treatment.

F) A) and D)
G) A) and C)

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The potential for hemolytic disease of the newborn occurs when


A) maternal Rh+ cells enter an Rh- fetus.
B) fetal Rh+ cells enter an Rh- mother.
C) maternal Rh- cells enter an Rh+ fetus.
D) fetal Rh- cells enter an Rh+ mother.
E) fetal Rh+ cells enter an Rh+ mother.

F) A) and B)
G) B) and D)

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Any heightened immune response resulting in tissue damage is called a/an


A) autoimmune disease.
B) immunodeficiency.
C) hypersensitivity.
D) transfusion reaction.
E) desensitization.

F) B) and C)
G) None of the above

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The allergen in poison ivy plants is an oil called urushiol.

A) True
B) False

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True

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