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MHC molecules are found on all of the following cells except


A) leukocytes.
B) eosinophils.
C) epithelial cells.
D) red blood cells.
E) islet of langerhans cells.

F) A) and C)
G) A) and B)

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T-cell response to T-cell-dependent antigens requires


A) typically a protein antigen.
B) binding of the T cell to a class II MHC receptor on a macrophage.
C) binding of the T cell to a site on the antigen.
D) interleukin-1 activating the T helper cell.
E) All of the choices are correct.

F) A) and C)
G) B) and D)

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E

Antitoxins


A) contain modified bacterial exotoxin molecules.
B) are always genetically engineered.
C) contain select antigenic components of a pathogen rather than whole cells or viruses.
D) confer passive immunity.
E) utilize DNA strands that will produce the antigen.

F) B) and D)
G) B) and C)

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You have received the first hepatitis A vaccine.It was required for your mission trip to Nicaragua in Central America,where hepatitis A is common.However,you never went back for the booster shot of the vaccine,which should have been received within 6 months of the initial vaccination.What statement accurately reflects your present immunity to this pathogen?


A) This is not a problem because the second dosage is just extra protection.Your immune status would be very high.
B) The one dosage is not enough because it only activated humoral immunity.The second dosage is to then activate cell-mediated immunity.The combination of the two immune responses gives you 100% coverage of immunity to hepatitis
C) Not a problem because at any time--in a year,5 years,etc.--you can go get the booster vaccine for hepatitis A and be fully covered by immunity.
D) You are at risk to get hepatitis A since your immune status is only partial.Not enough immune memory cells were produced since you received one dosage of vaccine,so you are likely to get the disease when exposed to the virus.

E) All of the above
F) C) and D)

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Fluzone is a brand name for a very commonly given influenza vaccine.The vaccine is prepared by first harvesting flu viruses in chicken embryos and then breaking apart virus particles into protein subunits,thereby inactivating the virus.Your friend refuses to get the vaccine.Which of these statements is the only valid reason for her not to get the flu vaccine?


A) She could catch the flu from the inactivated vaccine.
B) She could pass the virus onto her baby,causing the child to become autistic.
C) She could die from the vaccine.
D) She is allergic to eggs.

E) B) and C)
F) C) and D)

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An activated TH cell produces ___,which is a growth factor for T helper cells and cytotoxic T cells.


A) interleukin-1
B) interleukin-2
C) interleukin-12
D) antiserum
E) complement

F) D) and E)
G) A) and B)

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B

The immunoglobulin class that is the only one capable of crossing the placenta is


A) IgA
B) IgD
C) IgE
D) IgG
E) IgM

F) B) and D)
G) A) and E)

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A foreign molecule that causes a specific immune response is a/an


A) PAMP.
B) marker.
C) hapten.
D) antibody.
E) antigen.

F) D) and E)
G) A) and B)

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Acellular vaccines and subunit vaccines


A) contain modified bacterial exotoxin molecules.
B) are always genetically engineered.
C) contain select antigenic components of a pathogen rather than whole cells or viruses.
D) confer passive immunity.
E) utilize DNA strands that will produce the antigen.

F) A) and B)
G) B) and C)

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Helper T cells


A) secrete antibodies.
B) function in allergic reactions.
C) directly destroy target cells.
D) suppress immune reactions.
E) activate B cells and other T cells.

F) B) and E)
G) A) and E)

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A cytotoxic T lymphocyte,having been activated against a particular viral antigen,"sees" this same antigen on a host body cell.What will happen?


A) The cytotoxic T cell will produce antibodies against the antigen.
B) The antigen will move inside of the host body cell,thereby hiding from the cytotoxic T cell.
C) The cytotoxic T cell will produce proteins that cause the host body cell to die.
D) The cytotoxic body cell will activate B cells which then produce antibody against the antigen.

E) A) and B)
F) A) and C)

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The histocompatibility complex proteins function in


A) recognition of self.
B) antibody proliferation.
C) B-cell maturation.
D) T-cell maturation.

E) B) and D)
F) C) and D)

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A

Immunotherapy is the


A) use of antitoxins.
B) use of immune serum globulin.
C) conferring of passive immunity.
D) administering of preformed antibodies.
E) All of the choices are correct.

F) A) and B)
G) A) and C)

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An example of natural passive immunity would be


A) chickenpox infection,followed by lifelong immunity.
B) chickenpox vaccine triggering extended immunity to chickenpox.
C) giving a person immune serum globulins to chickenpox virus after exposure to the disease.
D) a fetus acquiring maternal IgG to the chickenpox virus across the placenta.

E) All of the above
F) B) and C)

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Which immunoglobulin class/es can fix complement?


A) IgM only
B) IgG only
C) IgD only
D) IgM and IgG
E) IgE and IgA

F) C) and D)
G) A) and C)

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Acquired specific immunity involves the response of


A) skin barriers.
B) B and T lymphocytes.
C) lysozyme.
D) mucus membranes.
E) interferon.

F) None of the above
G) B) and E)

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The immunoglobulin/s found on the surface of B cells is/are


A) IgM only.
B) IgG only.
C) IgD only.
D) IgM and IgD.
E) IgD and IgE.

F) C) and D)
G) All of the above

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An example of natural active immunity would be


A) chickenpox infection,followed by lifelong immunity.
B) chickenpox vaccine triggering extended immunity to chickenpox.
C) giving a person immune serum globulins to chickenpox virus after exposure to the disease.
D) a fetus acquiring maternal IgG to the chickenpox virus across the placenta.

E) A) and D)
F) None of the above

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As an adult who never developed chickenpox infection as a child,you elect to receive the protective vaccine against this pathogen at the age of 35.This vaccine will stimulate:


A) a primary immune response
B) latency
C) a secondary immune response
D) an anamnestic response

E) A) and D)
F) A) and C)

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One plasma cell will secrete antibodies of various classes,but the antibodies will all have the same specificity.

A) True
B) False

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